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EP2401365
REENGINEERING MRNA PRIMARY STRUCTURE FOR ENHANCED PROTEIN PRODUCTION
Filed
Feb 24, 2010
Technology
Chemistry · Biotechnology
UPC cases
15
Ownership history
As recorded at the EPO. Transfers made after the opposition period are recorded in national registers and may be missing here.
- The Scripps Research Institutesince Dec 2, 2011; EPO record ends Mar 3, 2017
Abstract
Described herein are rules to modify natural mRNAs or to engineer synthetic mRNAs to increase their translation efficiencies. These rules describe modifications to mRNA coding and 3' UTR sequences intended to enhance protein synthesis by: 1) decreasing ribosomal diversion via AUG or non-canonical initiation codons in coding sequences, and/or 2) by evading miRNA-mediated down-regulation by eliminating one or more miRNA binding sites in coding sequences.
From the international application WO2010098861
Litigation history
| Date | Case | Division | Type | Outcome | Parties |
|---|---|---|---|---|---|
| Oct 12, 2026 | UPC CoA 146/2026 | Court of Appeal | Appeal | Locked | Promosome LLC +9 |
Additional proceedings on this patent
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