UPC_CFI_187/2024

METHODS OF DETECTING NUCLEIC ACIDS IN INDIVIDUAL CELLS AND OF IDENTIFYING RARE CELLS FROM LARGE HETEROGENEOUS CELL POPULATIONS

InfringementMain Infringement ActionThe Hague LDInfringementCase Closed

Overview Decisions Reasoning Citations Documents Timeline

Parties

Claimants

Advanced Cell Diagnostics, Inc.

Reps: Judith Krens; Christopher Sharp; Kristina Cornish; Nicolas Bitsch

Respondents

Molecular Instruments, Inc.

Reps: Marianne Schaffner; Matthew Spencer; James Legg; Anne Marie Verschuur; Celine Bey

Judges

Edger Brinkman
Margot Kokke
Alima Zana
Michael Alt

Patents

EP1910572
EP2500439

CPC codes: C12Q1/6841, C12Q1/6837, C12Q1/6886, C12Q1/682, C12Q2600/158, C12Q1/6876

Technology area: Biotech · Diagnostics

Sector: Biotechnology

Outcome

Not infringedNot infringed

Filed: Apr 22, 2024

First decided: Nov 18, 2025

Language: English

The Hague Local Division decided in proceedings on infringement and counterclaim for revocation concerning Advanced Cell Diagnostics' RNAscope technology patents (EP 1 910 572 and EP 2 500 439) against Molecular Instruments; the decision addressed novelty, inventive step, and infringement of in situ hybridisation method claims.

Open on UPC Registry

Claims

At issue1

Not infringed1

Notes: The Hague LD found no infringement of EP1910572 and EP2500439 (RNAscope nucleic acid detection); analysis centered on independent claim 1 of EP572 with no infringement by equivalence found.