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UPC CoA 529/2024

Sep 13, 2024·EP3666797: ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)

Case details
Status
Case Closed
Action
Appeal
Category
Main Appeal
Parties
Claimants
Reps: Johannes Heselberger
Respondents
Reps: Niels Hoelder
Division
Court of Appeal
Judges
Technology
Biotechnology
Language
English
First decided
Nov 25, 2025
Claims
At issueall
Revokedall
Notes: Court of Appeal found EP 3 666 797 PCSK9 antibody patent lacked inventive step; patent revoked; specific claim numbers not enumerated in visible operative portion.
Decisions
  • 2025-11-25
    Patent maintainedAppeal decisionAppeal RoP220.1

    The Court of Appeal allowed Amgen's appeals in the revocation action and counterclaim for revocation concerning the PCSK9 antibody patent (Amgen v Sanofi and Regeneron). It set aside the Munich Central Division's decision revoking the patent, rejected the requests to revoke the patent in the UPC territories, and ordered Sanofi and Regeneron to bear the costs of both instances (EUR 1,375,000 each for first instance). The patent is maintained; the Court of Appeal found the claimed invention involved an inventive step.

    Legal issues:Claim interpretation (medical use-format claims)Added matterSufficiency of disclosureInventive step (PCSK9 antibodies)Reasonable expectation of success
Documents
Document titleDatePublic
action.issueDecision.decision2026-03-25Not public
Decision2026-03-25Public
Receipt2026-03-13Not public
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Application Appellant2026-03-13Not public
Receipt2026-03-11Not public
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Application Respondent2026-03-11Not public
Receipt2026-02-25Not public
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Application Appellant2026-02-25Not public
action.issueOrder.order2026-02-18Not public
Order2026-02-18Public
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Application document Appellant2026-02-05Not public
action.issueOrder.order2026-01-29Not public
Order2026-01-29Public
Receipt2026-01-26Not public
Cover sheet2026-01-26Not public
Other document Respondent2026-01-26Not public
Exhibit document Respondent2026-01-26Not public
Exhibit document Respondent2026-01-26Not public
Exhibit document Respondent2026-01-26Not public
Exhibit document Respondent2026-01-26Not public
Exhibit document Respondent2026-01-26Not public
Application document Respondent2026-01-26Not public
Receipt2026-01-26Not public
Cover sheet2026-01-26Not public
Application document Respondent2026-01-26Not public
action.communication.general2025-12-12Not public
Cover sheet2025-12-10Not public
Application document Respondent2025-12-10Not public
Receipt2025-12-10Not public
action.phaseChange.caseClose2025-11-25Not public
action.issueDecision.decision2025-11-25Not public
Decision2025-11-25Public
action.communication.general2025-11-24Not public
action.phaseChange.oralPhaseClose2025-09-22Not public
action.phaseChange.oralPhaseOpen2025-09-22Not public
action.phaseChange.writtenPhaseClose2025-09-22Not public
Hearing Reference2025-08-13Not public
Hearing Reference2025-08-13Not public
Schedule for oral hearing2025-08-05Public
Receipt2025-06-26Not public
Receipt2025-06-26Not public
C1282025-06-25Not public
C1302025-06-25Not public
C1232025-06-25Not public
C1282025-06-25Not public
C1242025-06-25Not public
C1182025-06-25Not public
C1252025-06-25Not public
2025.06.25 EP797 UPC appeal - letter to CoA commenting on OD decision2025-06-25Not public
C1262025-06-25Not public
C1272025-06-25Not public
C1182025-06-25Not public
C1322025-06-25Not public
C1292025-06-25Not public
C1312025-06-25Not public
C1332025-06-25Not public
Comments on the decision of the OD in opposition2025-06-25Not public
D102 - Decision Opposition Division of 21 May 2025 and minutes of the oral proceedings held on 31 March - 3 April 20252025-06-25Not public
Outcome of the Order2025-05-26Not public
order on time extension2025-05-26Public
Receipt2025-05-22Not public
2025.05.22 - Request for extension deadline for providing comments on OD decision - signed2025-05-22Not public
Summons2025-05-06Public
Response to order dated 17 April2025-04-29Not public
Annex - Evidence of prior commitment2025-04-29Not public
Reply to CoA Order2025-04-29Not public
case management order2025-04-17Public
Interim-Procedure-Closure2025-03-18Not public
Summon-Oral-Hearing2025-03-18Not public
order on IC2025-03-18Public
Template-Order2025-03-18Not public
Interim-Conference-Decision2025-03-18Not public
Acknowledgement-of-lodging2025-02-17Not public
C116a2025-02-17Not public
C121a2025-02-17Not public
C118a2025-02-17Not public
C117a2025-02-17Not public
C1172025-02-17Not public
C1202025-02-17Not public
C1212025-02-17Not public
2025.02.17 Statement of Response - signed2025-02-17Not public
C1192025-02-17Not public
C1222025-02-17Not public
C1162025-02-17Not public
C120a2025-02-17Not public
C115a2025-02-17Not public
C119a2025-02-17Not public
C122a2025-02-17Not public
C1152025-02-17Not public
C1182025-02-17Not public
Summons to oral hearing2025-02-11Public
2025.02.05 - Submission on appeal hearing date (Sanofi _ RGN)2025-02-05Not public
Flight reservation2025-02-05Not public
Reply Summons CoA2025-02-05Not public
Summons2025-01-30Not public
Comments2025-01-27Not public
Summonts TBA hearing2025-01-24Not public
Request rescheduling hearing2025-01-24Not public
Summons2025-01-22Not public
Panel-Appointment2024-12-11Not public
Acknowledgement-of-lodging2024-11-28Not public
Acknowledgement-of-lodging2024-11-15Not public
Statement of Grounds of Appeal2024-11-15Not public
D1012024-11-15Not public
Annex 3 - Consolidated list2024-11-15Not public
D1002024-11-15Not public
Panel-Appointment2024-10-07Not public
Receipt2024-10-07Not public
Acknowledgement-of-lodging2024-10-07Not public
Formal-checks_Notification-of-positive-outcome2024-10-07Not public
Acknowledgement-of-lodging2024-10-04Not public
Request_RgR16_1(b)_Change_details_representative_signed2024-10-04Not public
Rectified Statement of Appeal2024-10-02Not public
Statement of Appeal2024-10-02Not public
Proof of payment2024-10-02Not public
Formal-checks_Request-for-correction2024-09-24Not public
Acknowledgement-of-lodging2024-09-13Not public
Proof of payment2024-09-13Not public
Statement of Appeal2024-09-13Not public